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Article

Viral soluble decoy receptor as a novel treatment for IFN-I triggered diseases

2025-08-15

Abstract excerpt

Besides its antiviral action, type I interferon (IFN-I) plays a key role in triggering the inflammatory response and immunopathology in a group of autoinflammatory disorders known as interferonopathies. Current therapies for these diseases focus on blocking IFN-I signaling at different levels, but with incomplete success. Throughout evolution, to counteract the host immune response, poxviruses have developed decoy...

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Identifiers and source

Literature Corpus work
104a927f-200d-5837-9b9b-9b60966e38d2
DOI
10.1101/2025.08.12.669887
Open publication

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Viral soluble decoy receptor as a novel treatment for IFN-I triggered diseasesDOI 10.1101/2025.08.12.669887
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