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Article

Vaccinia virus strain Western Reserve protein B14 is an intracellular virulence factor.

The Journal of general virology - 1 Jun 2006

Chen Ron A-J, Jacobs Nathalie, Smith Geoffrey L

Abstract excerpt

A characterization of the B14R gene from Vaccinia virus (VACV) strain Western Reserve (WR) is presented. Computational analyses of the B14R gene indicated high conservation in orthopoxviruses but no orthologues outside the Poxviridae. To characterize the B14 protein, the B14R gene was expressed in Escherichia coli and recombinant protein was purified and used to generate a rabbit polyclonal antiserum. This...

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PMID: 16690909
DOI: 10.1099/vir.0.81736-0

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