Article
Inhibition of type I and type III interferons by a secreted glycoprotein from Yaba-like disease virus
22 May 2007
Abstract excerpt
Type I (IFN-alpha/beta) and type III (IFN-lambdas) IFNs are important components of the host antiviral response. Although type III IFNs possess intrinsic antiviral activity similar to that of type I IFNs, they signal through a specific unique receptor complex, and their functional importance for antiviral resistance is largely uncharacterized. Here, we report the first virus defense mechanism that directly...
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