Neurofibromatosis type 2: a new mechanism of tumor suppression.

doi:10.1016/S0166-2236(96)10044-8

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Article

Neurofibromatosis type 2: a new mechanism of tumor suppression.

Trends in neurosciences - 1 Sept 1996

Lutchman M, Rouleau G A

Abstract excerpt

Neurofibromatosis type 2 (NF2) is an autosomal dominant disease which predisposes primarily to CNS tumors such as schwannomas (vestibular and spinal), meningiomas, ependymomas and juvenile posterior lenticular opacities. Allelic losses on chromosome 22q first suggested the existence of a tumor su...

Topics

Genes, Neurofibromatosis 2
Humans
Models, Genetic
Mutation
Neurofibromatosis 2

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