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Article

Correlation of GC content with replication timing and repair mechanisms in weakly expressed E.coli genes.

Nucleic acids research - 25 Apr 1995

Deschavanne P, Filipski J

Abstract excerpt

Regional variations of DNA GC content are observed in species as different as S.cerevisiae and humans. In vertebrates and yeast they are correlated with replication timing; late replicating chromosomal regions are more AT-rich than early replicating regions. We show here that gene composition in E.coli also has long range variations which are similarly correlated with replication timing. We suggest that the...

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Identifiers

PMID: 7753625
DOI: 10.1093/nar/23.8.1350
PMCID: PMC306860

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