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Article

Biological activity of paramyxovirus fusion proteins: factors influencing formation of syncytia

1 Jul 1992

Abstract excerpt

The fusion (F) and hemagglutinin-neuraminidase (HN) glycoproteins of the paramyxovirus simian virus 5 (SV5) were expressed individually or coexpressed in CV-1 cells by using SV40-based vectors and recombinant vaccinia viruses. The extent of detectable fusion in a syncytium formation assay was found to be affected by the expression system used. In addition, when HN was coexpressed with F, it was found that the...

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PMID: 1602561
DOI: 10.1128/jvi.66.7.4564-4569.1992

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