Article
The C/EBP site in the feline immunodeficiency virus (FIV) long terminal repeat (LTR) is necessary for its efficient replication and is also involved in the inhibition of FIV LTR-directed gene expression by pseudorabies virus ICP4.
Virology - 20 Apr 1995
Kawaguchi Y, Tomonaga K, Maeda K, Ono M, Miyazawa T, Kohmoto M, Tohya Y, Mikami T
Abstract excerpt
We investigated effects of site-specific mutation of the putative C/EBP binding site in the feline immunodeficiency virus (FIV) long terminal repeat (LTR) on the basal promoter activity in Crandell feline kidney (CRFK) cells and on replication efficiency in CRFK cells and a T-lymphoblastoid cell...
Topics
- Animals
- Base Sequence
- CCAAT-Enhancer-Binding Proteins
- Cats
- Cell Line
- DNA Replication
- DNA, Viral
- DNA-Binding Proteins
- Gene Expression Regulation, Viral
- Immediate-Early Proteins
- Immunodeficiency Virus, Feline
- Molecular Sequence Data
- Mutation