Article
A thermoresistant strain of feline immunodeficiency virus (FIV) with an altered cytopathic effect and a restricted cell tropism.
Archives of virology - 1 Jan 1998
Alix C, Koehren F, Martin J P, Kirn A, Braunwald J
Abstract excerpt
A thermoresistant strain, designated m41, of feline immunodeficiency virus (FIV) was selected after 31 successive passages of chronically infected IRC4 cells at 41 degrees C. The wild-type virus (wt) which served as a control was cultivated the same number of times at 37 degrees C. In Crandell fe...
Topics
- Animals
- Bone Marrow Cells
- Cats
- Cell Line
- Cells, Cultured
- Cytopathogenic Effect, Viral
- Genes, env
- Hot Temperature
- Immunodeficiency Virus, Feline
- Kidney
- Leukocytes, Mononuclear
- Lymph Nodes
- Macrophages
- Molecular Sequence Data
- Phenotype
- Thymus Gland
- Virus Replication