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Article

[Molecular biology of beta A4 protein and Alzheimer disease].

Revue neurologique - 1 Jan 2000

Charnay Y, Vallet P G, Giannakopoulos P, Hof P R, Bouras C

Abstract excerpt

Senile plaques, neurofibrillary tangles and neuronal loss are the major histopathologic hallmarks of Alzheimer's disease. A prominent component of the senile plaques is a polypeptide (beta A4) of about 40 amino acids derived via proteolytic cleavage from a set of larger protein isoforms collectively referred to as the amyloid precursor protein (APP). The protein APP is a widely distributed transmembrane...

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Source

Identifiers

PMID: 7747007

Genes

APP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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