Article
A beta A4 amyloid precursor protein gene and Alzheimer's disease.
European journal of biochemistry - 1 Apr 1996
Hendriks L, Van Broeckhoven C
Abstract excerpt
Alzheimer's disease is a senile dementia caused by progressive neurodegeneration of the central nervous system. One of the most prominent pathological characteristics is beta A4 amyloid deposition in senile plaques in the brain parenchyma and in cerebral blood vessels. beta A4 amyloid is processed from a larger integral membrane protein, the beta A4 amyloid precursor protein. Different pathogenic mutations in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
