Article
A beta A4 amyloid precursor protein gene and Alzheimer's disease.
European journal of biochemistry - 1 Apr 1996
Hendriks L, Van Broeckhoven C
Abstract excerpt
Alzheimer's disease is a senile dementia caused by progressive neurodegeneration of the central nervous system. One of the most prominent pathological characteristics is beta A4 amyloid deposition in senile plaques in the brain parenchyma and in cerebral blood vessels. beta A4 amyloid is processe...
Topics
- Alzheimer Disease
- Amino Acid Sequence
- Amyloid beta-Peptides
- Amyloid beta-Protein Precursor
- Animals
- Apolipoproteins E
- Disease Models, Animal
- Down Syndrome
- Humans
- Molecular Sequence Data
- Mutation
- Protein Conformation
- Protein Processing, Post-Translational
- Vascular Diseases