Article
Masseter muscle rigidity associated with glycine1306-to-alanine mutation in the adult muscle sodium channel alpha-subunit gene.
Anesthesiology - 1 May 1995
Vita G M, Olckers A, Jedlicka A E, George A L, Heiman-Patterson T, Rosenberg H, Fletcher J E, Levitt R C
Abstract excerpt
BACKGROUND: Succinylcholine-induced masseter muscle rigidity (MMR) is a potentially life-threatening complication of anesthesia and is closely correlated with the heterogeneous disorder malignant hyperthermia (MH) susceptibility. MMR also is identified with a variety of neuromuscular disorders, including the myotonias, that are associated with abnormal in vitro contracture test (IVCT) results. Recently, mutations...
Topics
- Alanine
- Base Sequence
- Glycine
- Humans
- Malignant Hyperthermia
- Masseter Muscle
- Molecular Sequence Data
- Muscle Rigidity
- Muscles
- Mutation
- Polymerase Chain Reaction