Article
Leu110Pro substitution in the RhD polypeptide is responsible for the DVII category blood group phenotype.
American journal of hematology - 1 May 1995
Rouillac C, Le Van Kim C, Beolet M, Cartron J P, Colin Y
Abstract excerpt
The nucleotide sequence of the RhD transcripts from the reticulocytes of three unrelated variants with the DVII category blood group phenotype has been determined. Our results indicate that the expression of the low frequency antigen Rh40 and the lack of epD8 at the surface of these variant RhD p...
Topics
- Amino Acid Sequence
- Base Sequence
- DNA Primers
- DNA, Complementary
- Gene Expression
- Genetic Variation
- Humans
- Leucine
- Molecular Sequence Data
- Phenotype
- Point Mutation
- Polymerase Chain Reaction
- Proline
- Protein Structure, Secondary
- Reticulocytes
- Rh-Hr Blood-Group System