Molecular analysis of Rh polypeptides in a family with RhD-positive and RhD-negative phenotypes.

doi:10.1042/bj2990207

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Article

Molecular analysis of Rh polypeptides in a family with RhD-positive and RhD-negative phenotypes.

The Biochemical journal - 1 Apr 1994

Umenishi F, Kajii E, Ikemoto S

Abstract excerpt

To investigate the genetic basis of the Rh polypeptide gene, we attempted the isolation of cDNA clones for Rh polypeptide from a family with the RhD-positive and RhD-negative phenotypes using the reverse transcription (RT)-PCR method for each reticulocyte RNAs followed by subcloning. The isolated...

Topics

Base Sequence
Cloning, Molecular
DNA, Complementary
Female
Humans
Male
Molecular Sequence Data
Mutation
Pedigree
Peptides
Phenotype
RNA
Reticulocytes
Rh-Hr Blood-Group System

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