Article
Molecular basis of the D variant phenotypes DNU and DII allows localization of critical amino acids required for expression of Rh D epitopes epD3, 4 and 9 to the sixth external domain of the Rh D protein.
British journal of haematology - 1 May 1997
Avent N D, Jones J W, Liu W, Scott M L, Voak D, Flegel W A, Wagner F F, Green C
Abstract excerpt
The discovery of Rh partial D variant red cells by discrepant reactions with different monoclonal anti-D has demonstrated the range of Rh D epitopes that have arisen due to alterations in Rh D protein structure. There are two current classification systems, one which uses a nine epitope model (ep...
Topics
- Amino Acids
- Cloning, Molecular
- Epitope Mapping
- Epitopes
- Erythrocytes
- Humans
- Phenotype
- Point Mutation
- Rh-Hr Blood-Group System