Article
Rearrangements of the blood group RhD gene associated with the DVI category phenotype.
Blood - 15 Feb 1994
Mouro I, Le Van Kim C, Rouillac C, van Rhenen D J, Le Pennec P Y, Bailly P, Cartron J P, Colin Y
Abstract excerpt
The Rh (Rhesus) blood group antigens, D, Cc, and Ee, are carried by three unglycosylated membrane proteins of the human erythrocytes encoded by two highly related genes, D and CcEe. The major antigen, D, is a mosaic composed of at least nine determinants (epD1 through epD9). The lack of expression of some of these D epitopes at the surface of variant red blood cells defines the so-called D category phenotypes. In...
Topics
- Amino Acid Sequence
- Base Sequence
- Blotting, Southern
- DNA
- DNA Primers
- Erythrocyte Membrane
- Exons
- Gene Rearrangement
- Humans
- Molecular Sequence Data
- Phenotype