Article
Familial anticardiolipin antibodies and C4 deficiency genotypes that coexist with MHC DQB1 risk factors.
The Journal of rheumatology - 1 Feb 1995
Wilson W A, Scopelitis E, Michalski J P, Pierangeli S S, Silveira L H, Elston R C, Harris E N
Abstract excerpt
OBJECTIVE: To investigate the familial basis of antiphospholipid antibodies by studying putative risk factors at the C4 and MHC class II loci. METHODS: Autoimmune diseases, anticardiolipin (aCL) and other autoantibodies were studied in 38 first and 2nd degree family members of 3 index cases selec...
Topics
- Adolescent
- Adult
- Aged
- Aged, 80 and over
- Antibodies, Anticardiolipin
- Antiphospholipid Syndrome
- Autoantibodies
- Autoimmune Diseases
- Child
- Complement C4
- Female
- Genotype
- HLA-DQ Antigens
- HLA-DQ beta-Chains
- Haplotypes
- Humans
- Male
- Middle Aged
