Article
Familial anticardiolipin antibodies and C4 deficiency genotypes that coexist with MHC DQB1 risk factors.
The Journal of rheumatology - 1 Feb 1995
Wilson W A, Scopelitis E, Michalski J P, Pierangeli S S, Silveira L H, Elston R C, Harris E N
Abstract excerpt
OBJECTIVE: To investigate the familial basis of antiphospholipid antibodies by studying putative risk factors at the C4 and MHC class II loci. METHODS: Autoimmune diseases, anticardiolipin (aCL) and other autoantibodies were studied in 38 first and 2nd degree family members of 3 index cases selected for primary antiphospholipid syndrome (APS) and 33 controls. C4 protein phenotyping and restriction fragment length...
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