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Article

Interactions of vestigial and scabrous with the Notch locus of Drosophila melanogaster.

Genetics - 1 May 1990

Rabinow L, Birchler J A

Abstract excerpt

Interactions are described between the Notch locus of Drosophila melanogaster, and two other loci, scabrous and vestigial, which respectively affect the eyes and wings. The Notch locus is responsible for mediating decisions of cell fate throughout development in many different tissues. Mutations and duplications of vestigial and scabrous alter the severity of phenotypes associated with Notch mutations and...

Topics

Alleles
Animals
Cell Differentiation
Crosses, Genetic
DNA Transposable Elements
Drosophila melanogaster
Epidermal Growth Factor
Eye
Female
Genotype
Male
Multigene Family

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Phenotype

Wings, Animal

Source

Open in PubMed Open full text

Identifiers

PMID: 2160402
DOI: 10.1093/genetics/125.1.41
PMCID: PMC1204008

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2160402-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Interactions of vestigial and scabrous with the Notch locus of Drosophila melanogaster.PMID 2160402Read ↗

The effect of dominant vestigial alleles upon vestigial-mediated wing patterning during development of Drosophila melanogaster.Semantic proximity Read ↗

Genetic interactions among vestigial, hairy, and Notch suggest a role of vestigial in the differentiation of epidermal and neural cells of the wing and halter of Drosophila melanogaster.Semantic proximity Read ↗

Dachsous encodes a member of the cadherin superfamily that controls imaginal disc morphogenesis in Drosophila.Semantic proximity Read ↗

The functional organization of the vestigial locus in Drosophila melanogaster.Semantic proximity Read ↗

Drosophila eye development: Notch and Delta amplify a neurogenic pattern conferred on the morphogenetic furrow by scabrous.Semantic proximity Read ↗

Delta, notch, and shaggy: elements of a lateral signaling pathway in Drosophila.Semantic proximity Read ↗

The strawberry notch gene functions with Notch in common developmental pathways.Semantic proximity Read ↗

Notch pathway repression by vestigial is required to promote indirect flight muscle differentiation in Drosophila melanogaster.Semantic proximity Read ↗

deltex, a locus interacting with the neurogenic genes, Notch, Delta and mastermind in Drosophila melanogaster.Semantic proximity Read ↗

Notch signaling: control of cell communication and cell fate.Semantic proximity Read ↗

Different spatial and temporal interactions between Notch, wingless, and vestigial specify proximal and distal pattern elements of the wing in Drosophila.Semantic proximity Read ↗

Scalloped and strawberry notch are target genes of Notch signaling in the context of wing margin formation in Drosophila.Semantic proximity Read ↗

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