Changing Patterns of Transcriptional and Post-transcriptional Control of β-F1-ATPase Gene Expression during Mitochondrial Biogenesis in Liver

Abstract excerpt

To elucidate the mechanisms that regulate the expression of nuclear genes during biogenesis of mammalian mitochondria, the expression pattern of the beta-subunit of the ATP synthase gene has been characterized in rat liver between day 20 in utero and 12 weeks postnatal. The parallelism existing between transcriptional activity of the gene and the amount of beta-F1-ATPase protein in liver indicates that...

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