Article
In vivo analysis of key elements within the renin regulatory region.
Physiological genomics - 12 Nov 2008
Glenn Sean T, Jones Craig A, Pan Li, Gross Kenneth W
Abstract excerpt
Renin is responsible for initiating the enzymatic cascade that results in the production of angiotensin II, the major effector molecule of the renin-angiotensin system (RAS). Extensive information on the regulatory region of the renin gene has been derived by transient transfection studies in vitro, particularly using the As4.1 cell line. To verify key factors within the regulatory region of renin in vivo,...
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