Article
MASH-1: a marker and a mutation for mammalian neural crest development.
Perspectives on developmental neurobiology - 1 Jan 1994
Lo L, Guillemot F, Joyner A L, Anderson D J
Abstract excerpt
The ability to generate mice containing null mutations in any cloned gene promises new insights into the molecular control of mammalian neural crest development. This approach has recently been applied to MASH-1, a transcription factor in the bHLH family that is a mammalian homologue of the Drosophila proneural genes achaete-scute. In wild-type embryos, this gene is expressed early in the development of the...
Topics
- Adrenal Glands
- Animals
- Basic Helix-Loop-Helix Transcription Factors
- Biomarkers
- DNA-Binding Proteins
- Embryonic and Fetal Development
- Intestines
- Molecular Biology
- Mutation
- Nervous System
- Neural Crest