Article
Genomewide scan for affective disorder susceptibility Loci in families of a northern Swedish isolated population.
American journal of human genetics - 1 Feb 2005
Venken Tine, Claes Stephan, Sluijs Samuel, Paterson Andrew D, van Duijn Cornelia, Adolfsson Rolf, Del-Favero Jurgen, Van Broeckhoven Christine
Abstract excerpt
We analyzed nine multigenerational families with ascertained affective spectrum disorders in northern Sweden's geographically isolated population of Vasterbotten. This northern Swedish population, which originated from a limited number of early settlers approximately 8,000 years ago, is genetically more homogeneous than outbred populations. In a genomewide linkage analysis, we identified three chromosomal loci...
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