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BXD Recombinant Inbred Mice as a Model to Study Neurotoxicity

25 Nov 2021

Abstract excerpt

BXD recombinant inbred (RI) lines represent a genetic reference population derived from a cross between C57BL/6J mice (B6) and DBA/2J mice (D2), which through meiotic recombination events possesses recombinant chromosomes containing B6 or D2 haplotype segments. The quantitative trait loci (QTLs) are the locations of segregating genetic polymorphisms and are fundamental to understanding genetic diversity in human...

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PMID: 34944406
DOI: 10.3390/biom11121762

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