Article
Audiogenic seizures susceptibility in transgenic mice with fragile X syndrome.
Epilepsia - 1 Jan 2000
Musumeci S A, Bosco P, Calabrese G, Bakker C, De Sarro G B, Elia M, Ferri R, Oostra B A
Abstract excerpt
PURPOSE: To evaluate their susceptibility to audiogenic seizures, five groups of knockout mice with various forms of fragile X genetic involvement [hemizygous males (n = 46), and homozygous (n = 38) and heterozygous females (n = 45), and their normal male (n = 45) and female (n = 52) littermates] were studied. METHODS: All mouse groups were tested at ages 17, 22, 35, and 45 days. Audiogenic seizure susceptibility...
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