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Article

Founding BRCA1 mutations in hereditary breast and ovarian cancer in southern Sweden.

American journal of human genetics - 1 Mar 1996

Johannsson O, Ostermeyer E A, Håkansson S, Friedman L S, Johansson U, Sellberg G, Brøndum-Nielsen K, Sele V, Olsson H, King M C, Borg A

Abstract excerpt

Nine different germ-line mutations in the BRCA1 breast and ovarian cancer susceptibility gene were identified in 15 of 47 kindreds from southern Sweden, by use of SSCP and heteroduplex analysis of all exons and flanking intron region and by a protein-truncation test for exon 11, followed by direct sequencing. All but one of the mutations are predicted to give rise to premature translation termination and include...

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Identifiers

PMID: 8644702
PMCID: PMC1914564

Genes

BRCA1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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