Article
HPV16 E7 oncoprotein induces expression of a 110 kDa heat shock protein.
FEBS letters - 11 Sept 1995
Morozov A, Subjeck J, Raychaudhuri P
Abstract excerpt
Heat shock protein genes are induced by various kinds of stress. Besides stress, the heat shock family gene hsp70 has been shown to be induced by growth-stimulating agents such as the DNA virus oncoproteins and serum. Here, we report cloning of a novel cDNA that encodes a 100 kDa heat shock protein-related polypeptide as a human papillomavirus oncoprotein E7-inducible gene. E7 induces expression of this heat...
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