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Article

An epidemiologic assessment of genomic profiling for measuring susceptibility to common diseases and targeting interventions.

Genetics in medicine : official journal of the American College of Medical Genetics - 1 Jan 2000

Khoury Muin J, Yang Quanhe, Gwinn Marta, Little Julian, Dana Flanders W

Abstract excerpt

PURPOSE: The current clinical value of genomic profiling (testing for genotypes at multiple loci) for assessing susceptibility to common diseases and targeting behavioral and medical interventions is questionable. As common diseases result from many gene-environment interactions, epidemiologic studies should be used to examine the value of genomic profiling in terms of clinical validity (future disease positive...

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PMID: 14726808
DOI: 10.1097/01.gim.0000105751.71430.79

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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