Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Accuracy of predicting the genetic risk of disease using a genome-wide approach.

PloS one - 1 Jan 2008

Daetwyler Hans D, Villanueva Beatriz, Woolliams John A

Abstract excerpt

BACKGROUND: The prediction of the genetic disease risk of an individual is a powerful public health tool. While predicting risk has been successful in diseases which follow simple Mendelian inheritance, it has proven challenging in complex diseases for which a large number of loci contribute to t...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies
Share to Computational Biology
Share to Genetics, Population

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome, Human

Share to Models, Theoretical

Share to Polymorphism, Single Nucleotide

Share to Predictive Value of Tests

Share to Sample Size

Source

Open in PubMed Open full text

Identifiers

PMID: 18852893
DOI: 10.1371/journal.pone.0003395
PMCID: PMC2561058

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-18852893-2026-09-04.1. Manifest publication-graph-cohort-2026-09-04.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Accuracy of predicting the genetic risk of disease using a genome-wide approach.PMID 18852893Read ↗

A unifying framework for evaluating the predictive power of genetic variants based on the level of heritability explained.Semantic proximity Read ↗

Prediction of individual genetic risk to disease from genome-wide association studies.Semantic proximity Read ↗

Genetic risk prediction in complex disease.Semantic proximity Read ↗

A deterministic equation to predict the accuracy of multi-population genomic prediction with multiple genomic relationship matrices.Semantic proximity Read ↗

[Methodological challenges for genome-based prediction of diseases].Semantic proximity Read ↗

Evaluating genetic-based disease prediction approaches through simulation.Semantic proximity Read ↗

Prediction of individual genetic risk of complex disease.Semantic proximity Read ↗

Evaluating Genetic-Based Disease Prediction Approaches Through SimulationSemantic proximity Read ↗

Developing and evaluating polygenic risk prediction models for stratified disease prevention.Semantic proximity Read ↗

The contribution of genetic variants to disease depends on the ruler.Semantic proximity Read ↗

A new explained-variance based genetic risk score for predictive modeling of disease risk.Semantic proximity Read ↗

A better design for stratified medicine based on genomic predictionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.