Article
Accuracy of predicting the genetic risk of disease using a genome-wide approach.
PloS one - 1 Jan 2008
Daetwyler Hans D, Villanueva Beatriz, Woolliams John A
Abstract excerpt
BACKGROUND: The prediction of the genetic disease risk of an individual is a powerful public health tool. While predicting risk has been successful in diseases which follow simple Mendelian inheritance, it has proven challenging in complex diseases for which a large number of loci contribute to the genetic variance. The large numbers of single nucleotide polymorphisms now available provide new opportunities for...
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