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Article

Evaluation of the discriminative accuracy of genomic profiling in the prediction of common complex diseases.

European journal of human genetics : EJHG - 1 Apr 2010

Moonesinghe Ramal, Liu Tiebin, Khoury Muin J

Abstract excerpt

Genetic testing for susceptibility to common diseases based on a combination of genetic markers may be needed because the effect size associated with each genetic marker is small. Whether or not a genome profile based on a combination of markers could yield a useful test can be evaluated by assessing the discriminative accuracy. The authors present a simple method to calculate the clinical discriminative accuracy...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19935832
DOI: 10.1038/ejhg.2009.209
PMCID: PMC2987256

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