Article
Evidence that F plasmid transfer replication underlies apparent adaptive mutation.
Science (New York, N.Y.) - 21 Apr 1995
Galitski T, Roth J R
Abstract excerpt
An Escherichia coli K12 strain, FC40, has been used extensively in the analysis of adaptive mutability. This strain carries a revertible mutant lac allele on an F plasmid and accumulates Lac+ (lactose utilizing) revertants, but not unselected mutants, when placed on selective medium. These adaptive mutations are a subset of spontaneous types and their formation depends on the RecABC functions. Data presented here...
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