Article
Recombination speeds adaptation by reducing competition between beneficial mutations in populations of Escherichia coli.
PLoS biology - 1 Sept 2007
Cooper Tim F
Abstract excerpt
Identification of the selective forces contributing to the origin and maintenance of sex is a fundamental problem in biology. The Fisher-Muller model proposes that sex is advantageous because it allows beneficial mutations that arise in different lineages to recombine, thereby reducing clonal interference and speeding adaptation. I used the F plasmid to mediate recombination in the bacterium Escherichia coli and...
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