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Article

A space-time process model for the evolution of DNA sequences.

Genetics - 1 Feb 1995

Yang Z

Abstract excerpt

We describe a model for the evolution of DNA sequences by nucleotide substitution, whereby nucleotide sites in the sequence evolve over time, whereas the rates of substitution are variable and correlated over sites. The temporal process used to describe substitutions between nucleotides is a continuous-time Markov process, with the four nucleotides as the states. The spatial process used to describe variation and...

Topics

Animals
Biological Evolution
Codon
DNA, Mitochondrial
Genetic Variation
Likelihood Functions
Markov Chains
Models, Genetic
Primates

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 7713447
DOI: 10.1093/genetics/139.2.993
PMCID: PMC1206396

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7713447-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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