Article
A multivariate analysis of repeated measures: linkage of the albinism gene (Tyr) to a QTL influencing ethanol-induced anesthesia in laboratory mice.
Psychiatric genetics - 1 Jan 1994
Markel P D, Corley R P
Abstract excerpt
We propose the use of multivariate analysis of variance in order to address linkage relationships between a genetic marker and a phenotype that is specified by multiple variables. Moreover, enhanced power of a linkage model that simultaneously accounts for environmental factors is demonstrated in the present study. This strategy was used to establish linkage of a quantitative trait locus influencing...
Topics
- Albinism
- Anesthetics
- Animals
- Crosses, Genetic
- Defecation
- Drug Resistance
- Environment
- Ethanol
- Female
- Genetic Linkage
- Genetic Markers
- Male
