Article
Ontogeny of Reproductive Abnormalities Induced by Deregulation of Anti-Müllerian Hormone Expression in Transgenic Mice
1 Feb 1995
Abstract excerpt
Anti-müllerian hormone, normally responsible for the regression of müllerian ducts in male fetuses, induces stunting, germ cell loss, and seminiferous tubule formation in ovaries of bovine freemartin fetuses and of transgenic mice, which express the human anti müllerian hormone gene under the control of the metallothionein promoter. Because the latter have been studied only after birth, we undertook a detailed...
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