Article
Human interleukin-4 and variant R88Q: phasing X-ray diffraction data by molecular replacement using X-ray and nuclear magnetic resonance models.
Journal of molecular biology - 24 Mar 1995
Müller T, Oehlenschläger F, Buehner M
Abstract excerpt
The structure of recombinant human interleukin-4 (hIL-4) has been determined by both NMR and X-ray diffraction methods in several laboratories, including ours. The X-ray and NMR structures were successfully applied for solving the X-ray crystal structure by molecular replacement. Due to the small...
Topics
- Computer Simulation
- Crystallography, X-Ray
- Genetic Variation
- Humans
- Interleukin-4
- Magnetic Resonance Spectroscopy
- Models, Molecular
- Molecular Sequence Data
- Mutation
- Protein Binding
- Protein Conformation
- Recombinant Proteins
- Software