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Article

Human interleukin-4 and variant R88Q: phasing X-ray diffraction data by molecular replacement using X-ray and nuclear magnetic resonance models.

Journal of molecular biology - 24 Mar 1995

Müller T, Oehlenschläger F, Buehner M

Abstract excerpt

The structure of recombinant human interleukin-4 (hIL-4) has been determined by both NMR and X-ray diffraction methods in several laboratories, including ours. The X-ray and NMR structures were successfully applied for solving the X-ray crystal structure by molecular replacement. Due to the small size of the hIL-4 molecule (129 residues) and its lack of structural diversity (4-helix bundle), this task was...

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PMID: 7707380
DOI: 10.1006/jmbi.1994.0144

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