Article
Direct tumorigenic conversion of human gallbladder carcinoma cells by v-src but not by activated c-H-ras oncogene.
International journal of cancer - 10 Apr 1995
Tatsumoto T, Nakano S, Shimizu K, Ono M, Esaki T, Ohshima K, Niho Y
Abstract excerpt
The roles of activated ras and src oncogene products in the acquisition of fully neoplastic phenotype by human gallbladder adenocarcinoma cells were investigated by co-transfecting non-tumorigenic HAG-I human gallbladder carcinoma cells with the pSV2neo plasmid and a plasmid carrying either activ...
Topics
- Adenocarcinoma
- Animals
- Benzoquinones
- Blotting, Northern
- Blotting, Southern
- Cell Adhesion
- Cell Division
- Cell Transformation, Neoplastic
- Disease Progression
- Gallbladder Neoplasms
- Gene Expression Regulation, Neoplastic
- Genes, ras
- Genes, src
- Humans
- Immunoblotting
- Karyotyping
- Lactams, Macrocyclic
- Mice