Article
Transcription initiation from within P elements generates hypomorphic mutations in Drosophila melanogaster.
Genetics - 1 Jul 2011
LaFave Matthew C, Sekelsky Jeff
Abstract excerpt
Numerous transposable element insertions in Drosophila melanogaster cause hypomorphic mutations. We report that transcription initiation within a region found in many P-element constructs provides an explanation for why some gene function is retained. We detected evidence of this transcription in four different types of P constructs, regardless of whether the insertion was in a coding exon, intron, 5'...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
