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Article

Chronic hepatitis C virus infections: predictive value of genotype and level of viraemia on disease progression and response to interferon alpha.

Gut - 1 Mar 1995

Booth J C, Foster G R, Kumar U, Galassini R, Goldin R D, Brown J L, Thomas H C

Abstract excerpt

The effects of hepatitis C virus genotype and viraemia on disease outcome in patients with chronic hepatitis C virus infection were studied. Patients infected with genotype 1 tended to develop more severe disease, and to respond less well to interferon (IFN) treatment, but no pretreatment variable successfully predicted either the severity of the disease or the response to IFN. Failure to eliminate the virus...

Topics

Base Sequence
Cross-Over Studies
Disease Progression
Genotype
Hepacivirus
Hepatitis C
Hepatitis, Chronic
Humans
Interferon-alpha
Molecular Sequence Data
Patient Selection

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Prognosis

Time Factors

Treatment Outcome

Viremia

Source

Open in PubMed Open full text

Identifiers

PMID: 7698703
DOI: 10.1136/gut.36.3.427
PMCID: PMC1382459

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7698703-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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