Article
HCV genotypes--role in pathogenesis of disease and response to therapy.
Bailliere's best practice & research. Clinical gastroenterology - 1 Apr 2000
Webster G, Barnes E, Brown D, Dusheiko G
Abstract excerpt
Hepatitis C virus (HCV) shows considerable variation in its genomic structure, allowing classification into six main genotypes. Epidemiological studies have shown marked differences in genotype distribution by geographical region, and between patient groups. Improved understanding of the rate of nucleotide sequence mutation in HCV has allowed the approximate time of divergence of major genotypes to be estimated,...
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