Article
Predictive factors in the response to interferon therapy in chronic hepatitis C.
Liver - 1 Apr 1995
Yoshioka K, Higashi Y, Yamada M, Aiyama T, Takayanagi M, Tanaka K, Okumura A, Iwata K, Kakumu S
Abstract excerpt
Factors predicting the efficacy of interferon therapy were statistically analyzed on 111 patients with chronic hepatitis C. Of the treated patients (total doses of interferon; 96-468 MU), 35 (31.5%) had a long-term remission. On multivariate analysis, hepatitis C virus genotype (p < 0.0001), histological diagnosis (p < 0.05), fibrosis score of histological activity index (p < 0.01) and source of infection (p <...
Topics
- Adult
- Analysis of Variance
- Base Sequence
- Female
- Genotype
- Hepacivirus
- Hepatitis C
- Hepatitis, Chronic
- Humans
- Interferons
- Male
- Middle Aged
