Article
Viral and host factors in the prediction of response to interferon-alpha therapy in chronic hepatitis C after long-term follow-up.
Journal of viral hepatitis - 1 Nov 1998
Knolle P A, Kremp S, Höhler T, Krummenauer F, Schirmacher P, Gerken G
Abstract excerpt
Acute infection with hepatitis C virus (HCV) develops into a chronic hepatitis in about 50-70% of patients. Treatment of these patients with interferon-alpha (IFN-alpha) results in a sustained long-term response in only 15-20% but causes numerous unwanted side-effects in a higher percentage of patients. The aim of our study was to define host or viral parameters that would allow identification of responders and...
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