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Article

Viral and host factors in the prediction of response to interferon-alpha therapy in chronic hepatitis C after long-term follow-up.

Journal of viral hepatitis - 1 Nov 1998

Knolle P A, Kremp S, Höhler T, Krummenauer F, Schirmacher P, Gerken G

Abstract excerpt

Acute infection with hepatitis C virus (HCV) develops into a chronic hepatitis in about 50-70% of patients. Treatment of these patients with interferon-alpha (IFN-alpha) results in a sustained long-term response in only 15-20% but causes numerous unwanted side-effects in a higher percentage of pa...

Topics

Adult
Antiviral Agents
Female
Follow-Up Studies
Genotype
HLA-DR Antigens
Hepacivirus
Hepatitis C, Chronic
Humans
Interferon-alpha
Male
Middle Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

RNA, Viral

Treatment Outcome

Tumor Necrosis Factor-alpha

Viral Load

Viremia

Source

Identifiers

PMID: 9857349
DOI: 10.1046/j.1365-2893.1998.00127.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9857349-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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