Article
Viral factors affecting the outcome of therapy for chronic hepatitis C.
Reviews in gastroenterological disorders - 1 Jan 2004
Fried Michael W
Abstract excerpt
The advent of sensitive virologic assays to quantify hepatitis C virus (HCV) RNA and to differentiate specific genotypes of HCV has greatly expanded our understanding of the pathogenesis of chronic hepatitis C. These molecular virologic techniques are regularly employed to assist with management decisions regarding antiviral therapy. Genotype is the strongest predictor of a sustained virologic response (SVR). The...
Topics
- Drug Therapy, Combination
- Female
- Genotype
- Hepacivirus
- Hepatitis C, Chronic
- Humans
- Interferon alpha-2
- Interferon-alpha
- Male
- Pharmacogenetics
- Polyethylene Glycols
- RNA, Viral
- Recombinant Proteins
- Ribavirin
- Risk Assessment
- Sensitivity and Specificity
- Severity of Illness Index
- Treatment Outcome
