Article
Genotype distribution of angiotensin-converting enzyme polymorphism in Australian healthy and coronary populations and relevance to myocardial infarction and coronary artery disease.
Arteriosclerosis, thrombosis, and vascular biology - 1 Jan 1996
Wang X L, McCredie R M, Wilcken D E
Abstract excerpt
Angiotensin-converting enzyme is a key component of the renin-angiotensin system that plays an important role in cardiovascular regulation. An association between the angiotensin-converting enzyme insertion/deletion (I/D) polymorphism and increased coronary risk has been found in some studies but not in others. To explore this further in an Australian white population, we compared the ACE genotype distribution in...
Topics
- Adolescent
- Adult
- Aged
- Alleles
- Australia
- Child
- Coronary Disease
- Female
- Gene Frequency
- Genotype
- Humans
- Male
- Middle Aged
- Myocardial Infarction
- Peptidyl-Dipeptidase A
- Polymorphism, Genetic
- White People