Article
Human platelet phenolsulfotransferases: cDNA cloning, stable expression in V79 cells and identification of a novel allelic variant of the phenol-sulfating form.
Biochemical and biophysical research communications - 17 Mar 1995
Jones A L, Hagen M, Coughtrie M W, Roberts R C, Glatt H
Abstract excerpt
We have isolated cDNA clones encoding phenol- and monoamine-sulfating phenolsulfotransferases, using the reverse transcription-polymerase chain reaction method with human platelet mRNA as template. These cDNAs were stably expressed in the Chinese hamster fibroblast cell line V79 and their substrate specificities towards known sulfotransferase isoenzyme-selective compounds determined. The nucleotide and derived...
Topics
- Alleles
- Amino Acid Sequence
- Animals
- Arylsulfotransferase
- Base Sequence
- Blood Platelets
- Cricetinae
- Cricetulus
- DNA Primers
- Humans
- Molecular Sequence Data
