Development of coronary atherosclerosis in swine with severe hypercholesterolemia. Lack of influence of von Willebrand factor or acute intimal injury.

doi:10.1161/01.atv.6.2.155

Back to search

Article

Development of coronary atherosclerosis in swine with severe hypercholesterolemia. Lack of influence of von Willebrand factor or acute intimal injury.

Arteriosclerosis (Dallas, Tex.) - 1 Jan 2000

Griggs T R, Bauman R W, Reddick R L, Read M S, Koch G G, Lamb M A

Abstract excerpt

The development of coronary atherosclerosis in response to acute intimal injury and severe hypercholesterolemia was studied in 18 swine, nine normal and nine with von Willebrand's disease, an inherited disorder affecting platelet-vessel wall interactions. The left anterior descending coronary art...

Topics

Animals
Arteriosclerosis
Cholesterol
Coronary Vessels
Diet, Atherogenic
Heart Diseases
Hypercholesterolemia
Mathematics
Phenotype
Swine
von Willebrand Factor

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.