A forward mutation assay in phage T4: application to gene 42 mutator mutations.

doi:10.1016/0921-8777(93)90007-4

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Article

A forward mutation assay in phage T4: application to gene 42 mutator mutations.

Mutation research - 1 Oct 1993

Ji J, Mathews C K

Abstract excerpt

A forward mutation assay was developed to study mutagenic specificity induced by temperature-sensitive alleles of bacteriophage T4 gene 42, which encodes a thermolabile deoxycytidylate hydroxymethylase. Thymidine kinase (tk) mutations induced by T4 ts B3 at a semi-permissive temperature (34 degre...

Topics

Bacteriophage T4
Base Sequence
DNA Mutational Analysis
DNA, Viral
Genes, Viral
Hydroxymethyl and Formyl Transferases
Molecular Sequence Data
Mutagenesis
Phenotype
Polymerase Chain Reaction
Temperature
Thymidine Kinase
Transferases

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