Article
A forward mutation assay in phage T4: application to gene 42 mutator mutations.
Mutation research - 1 Oct 1993
Ji J, Mathews C K
Abstract excerpt
A forward mutation assay was developed to study mutagenic specificity induced by temperature-sensitive alleles of bacteriophage T4 gene 42, which encodes a thermolabile deoxycytidylate hydroxymethylase. Thymidine kinase (tk) mutations induced by T4 ts B3 at a semi-permissive temperature (34 degrees C) were selected under near-ultraviolet light on synthetic agar plates containing bromodeoxyuridine, and sequenced...
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