Article
A highly divergent antigenic site of foot-and-mouth disease virus retains its immunodominance.
Viral immunology - 1 Jan 1995
Borrego B, Camarero J A, Mateu M G, Domingo E
Abstract excerpt
The ability of a highly divergent antigenic site of foot-and-mouth disease virus (FMDV) of serotype C to elicit neutralizing antibodies has been evaluated in mice and rabbits. The viruses compared, FMDV C-S8c1 and HR, differ in a single amino acid replacement in their capsid proteins, but represent two extreme antigenic specificities of the major antigenic site A of FMDV type C. Both, studies of...
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