Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Phenotypic characterization of the human fibrous histiocytoma giant cell tumor (GCT) cell line and its cytokine repertoire.

Experimental hematology - 1 Sept 1993

Liesveld J L, Rush S, Kempski M C, Turner A R, Brennan J K, Gasson J C, Abboud C N

Abstract excerpt

The pleiotropic nature of malignant fibrous histiocytomas (MFH) is manifested as mixed cellular infiltrates consisting of myofibroblasts, histiomonocytes, and neutrophils. We detail in this report the phenotypic characteristics of the human fibrous histiocytoma giant cell tumor (GCT) cell line that establish its mesenchymal origin. The latter is underscored by the ability of GCT cells to express mRNA for...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to TNF gene
Share to Cytokines
Share to Gene Expression

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Phenotype

Share to Polymerase Chain Reaction

Share to RNA, Messenger

Share to Tumor Cells, Cultured

Share to Tumor Necrosis Factor-alpha

Source

Identifiers

PMID: 7689482

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Phenotypic characterization of the human fibrous histiocytoma giant cell tumor (GCT) cell line and its cytokine repertoire.PMID 7689482Read ↗

Giant cell tumor of bone: A unique paradigm of stromal–hematopoietic cellular interactionsSemantic proximity Read ↗

Malignant fibrous histiocytoma: a proposed cellular origin and identification of its characterizing gene transcripts.Semantic proximity Read ↗

Novel CSF1R-positive tenosynovial giant cell tumor cell lines and their pexidartinib (PLX3397) and sotuletinib (BLZ945)-induced apoptosisSemantic proximity Read ↗

Phenotypic characterisation of mononuclear and multinucleated cells of giant cell tumour of bone.Semantic proximity Read ↗

Interactions in CSF1-driven Tenosynovial Giant Cell TumorsSemantic proximity Read ↗

Central giant cell granulomas of the jaws: phenotype and proliferation‐associated markersSemantic proximity Read ↗

Central giant cell granulomas of the jaws stromal cells harbour mutations and have osteogenic differentiation capacity, in vivo and in vitro.Semantic proximity Read ↗

Orbital pseudotumor can be a localized form of granulomatosis with polyangiitis as revealed by gene expression profilingSemantic proximity Read ↗

Multinucleated giant cell phenotype in response to stimulation.Semantic proximity Read ↗

The broad spectrum of cytokine gene expression by myoid cells from the human marrow microenvironment.Semantic proximity Read ↗

Murine endothelioma cell lines transformed by polyoma middle T oncogene as target for and producers of cytokinesSemantic proximity Read ↗

Expression of Osteoclast Differentiation Signals by Stromal Elements of Giant Cell TumorsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.