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Article

Malignant fibrous histiocytoma: a proposed cellular origin and identification of its characterizing gene transcripts.

International journal of oncology - 1 Aug 2003

Gazziola Cinzia, Cordani Nicoletta, Wasserman Bruna, Carta Sonia, Colombatti Alfonso, Perris Roberto

Abstract excerpt

Although malignant fibrous histiocytoma (MFH) is one of the most diffuse and highly aggressive tumors among soft tissue sarcomas in adults, it is poorly characterized from the molecular point of view. The overt lack of expression of phenotypic markers in MFH cells and the hypothesis that MFH may originate from transformed multipotent stem/progenitor cells with mesenchymal features has led us to investigate this...

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PMID: 12851683

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MSC

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