Phenotypic characterisation of mononuclear and multinucleated cells of giant cell tumour of bone.

doi:10.1016/0169-6009(92)90820-4

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Article

Phenotypic characterisation of mononuclear and multinucleated cells of giant cell tumour of bone.

Bone and mineral - 1 Jan 1992

Joyner C J, Quinn J M, Triffitt J T, Owen M E, Athanasou N A

Abstract excerpt

Studies were carried out on 3 giant cell tumours of bone (GCTB) to characterise further the cells forming the distinctive mononuclear and multinucleated components. Samples of tumours were grown as explants in vitro and implanted subcutaneously in athymic mice. Cells were characterised in terms of their cell morphology and cytochemical, antigenic and functional phenotype. In culture, giant cells formed a...

Topics

Adult
Animals
Antigens, CD
Antigens, Differentiation, Myelomonocytic
Bone Neoplasms
Bone Resorption
Calcitonin
Cell Nucleus
Fibroblasts
Giant Cell Tumors
HLA-DR Antigens

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Histocompatibility Antigens

Humans

Immunoenzyme Techniques

Immunohistochemistry

Immunophenotyping

Leukocyte Common Antigens

Macrophages

Source

Open in PubMed

Identifiers

PMID: 1531620
DOI: 10.1016/0169-6009(92)90820-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1531620-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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