Article
Deletion of chromosome 11 and of 14q sequences in neuroblastoma.
Genes, chromosomes & cancer - 1 May 1993
Srivatsan E S, Ying K L, Seeger R C
Abstract excerpt
Restriction fragment length polymorphism (RFLP) analysis carried out on 45 primary neuroblastomas showed deletion of chromosome 11 sequences in 12 of 37 (32%) informative cases. Both 11p and 11q probes were informative in seven tumors; loss of all of chromosome 11, of only 11p sequences, and of only 11q sequences was observed in 4, 1, and 2 tumors, respectively. A cytogenetic abnormality involving translocation...
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